No hepatitis recurrence using combination prophylaxis in HBV-positive liver transplant recipients with YMDD mutants
نویسندگان
چکیده
منابع مشابه
Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis.
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. The aim of this study was to determine the prevalence of HBV S gene mutations in liver transplant recipients who developed recurrent hepatitis B despite HBIG prophylaxis, and to determine if these mutations can revert after withdrawal of HBIG. The e...
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Although the overall incidence of fungal infections in liver transplant recipients has declined, these infections still contribute significantly to the morbidity and mortality of patients with risk factors for infection. Although antifungal prophylaxis has been widely studied and practiced, no consensus exists on which patients should receive prophylaxis, with which agent, and for what duration...
متن کاملDoes pre-liver transplant HBV DNA level affect HBV recurrence or survival in liver transplant recipients receiving HBIg and nucleos(t)ide analogues?
BACKGROUND AND AIMS The risk of recurrent hepatitis B virus (HBV) infection and prognosis of liver transplantation in patients with HBV has dramatically changed with the use of prophylaxis including hepatitis B immune globulin (HBIg) and antiviral agents. METHODS This study analyzes the prognostic value of HBV DNA level before orthotopic liver transplantation (OLT) and the effect of HBV proph...
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A high incidence of HBV-related hepatitis is associated with the use of HBsAg-positive marrow for transplantation, and the high viral load in the donor appears to predispose recipients to the development of HBV-related hepatitis postransplant. Preemptive use of lamivudine has proved to reduce hepatitis B exacerbation in HBsAgpositive recipients of allogeneic HCT. Since 2000, the policy in our m...
متن کاملOutcomes of antifungal prophylaxis in high-risk liver transplant recipients.
Antifungal prophylaxis for liver transplant recipients (LTRs) is common among patients considered at high risk of infection, but optimal prophylaxis duration and drug has not been defined. This study aimed to assess the effects of 14 days of antifungal therapy prophylaxis in reducing proven invasive fungal infections (IFI) in high-risk subjects. Eligible subjects who met 2 or more risk criteria...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2005
ISSN: 0934-0874,1432-2277
DOI: 10.1111/j.1432-2277.2004.00034.x